{"id":232,"date":"2017-04-01T13:29:16","date_gmt":"2017-04-01T13:29:16","guid":{"rendered":"http:\/\/apmaldi.com\/main\/?page_id=232"},"modified":"2017-06-16T17:09:39","modified_gmt":"2017-06-16T17:09:39","slug":"apmaldi-ng-hr","status":"publish","type":"page","link":"https:\/\/www.apmaldi.com\/main\/products\/apmaldi-ng-hr\/","title":{"rendered":"AP\/MALDI (ng) HR"},"content":{"rendered":"<h2>What is AP-MALDI?<\/h2>\n<p>The AP-MALDI (Atmospheric Pressure, Matrix Assisted Laser Desorption\/Ionization) source has been our signature product since the inception of the company. Currently in its\u2019 fifth generation -called AP-MALDI (ng) HR &#8211; our AP-MALDI ion source uses several key pieces of technology MassTech has developed over years of work with this product. Furthermore, as the AP-MALDI operates at atmospheric pressure (requiring zero pumping time after installation) samples are not required to be vacuum compatible. This gives you the ability to use volatile or semi-volatile solvents and matrices in your sample, allowing for new and non-traditional MALDI applications.<\/p>\n<p>The AP-MALDI source is compatible with Mass Spectrometers from all major Mass Spectrometer manufacturers. Due to the atmospheric pressure interface, you can switch from ESI to AP-MALDI in minutes, if not seconds! For labs with occasional MALDI needs, or for labs without a dedicated MALDI Mass Spectrometer, the AP-MALDI source is the perfect solution.<\/p>\n<p>At MassTech, we have developed applications using the AP-MALDI in conjunction with instruments with MS\/MS capabilities, such as our own MT Explorer 50, allowing us to do MALDI MS\/MS and do work such as detection and even identification of bacteria and other biological samples. If your instrument has accurate mass measurement capability, with the AP-MALDI you can do accurate mass MALDI. As a result, we have seen excellent results with instruments such as the Thermo QExactive Orbitrap and the latest Agilent 6000 series.<\/p>\n<p>The AP-MALDI is sold world-wide through our network of distributors. Within the Continental United States, you can contact us directly for a price quote. For international deliveries, all quotes requests to msms@apmaldi.com will be redirected to the appropriate distributor. Agilent representatives can contact us directly for preferential pricing. There is a one-time installation\/training fee for these units.<\/p>\n<h2>What is HR?\u00a0 UHR?\u00a0 (ng)?<\/h2>\n<p>The current AP\/MALDI is on its fifth generation.\u00a0 Along with improvements such as a solid state Nd:YAG laser, which should last for well over a decade, we have focused on usability and ease of installation with the Next Generation (ng) AP\/MALDI.<\/p>\n<p>Those improvements include: an internally stored solid state laser and laser controller.\u00a0 Enhanced accuracy micro-step stages.\u00a0 Externally mounted controls for laser focus and position as well as camera focus and position.\u00a0 Enhanced optical components to produce smaller spot sizes.<\/p>\n<p>The difference between HR and UHR is with the optical package installed in the system.\u00a0 The UHR optical package allows for sub-10 micron laser dot size (imaging resolution).\u00a0 The HR optical package can focus up to 50 micron.\u00a0 For work that does not require sub-10 micron resolution, the HR package is an economical option that provides the user with every other improvement that the Next Generation platform delivers.<\/p>\n<h2>Why select AP MALDI?<\/h2>\n<ul>\n<li>It is the most cost effective way to do MALDI MS\/MS<\/li>\n<li>It is sensitive &#8211; users can detect peptides at attmole level<\/li>\n<li>Easily interchangeable with ESI in just minutes<\/li>\n<li>\u201cSofter\u201d ionization (i.e., mostly +1 charge ions produced) due to fast thermalization of internal energies at atmospheric conditions<\/li>\n<li>High throughput applications<\/li>\n<li>Lower lifetime ownership cost<\/li>\n<\/ul>\n<h2>Compatible with<\/h2>\n<ul>\n<li>Agilent<\/li>\n<li>Bruker<\/li>\n<li>JEOL<\/li>\n<li>Sciex<\/li>\n<li>Shimadzu<\/li>\n<li>Thermo<\/li>\n<li>Waters<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>What is AP-MALDI? The AP-MALDI (Atmospheric Pressure, Matrix Assisted Laser Desorption\/Ionization) source has been our signature product since the inception of the company. Currently in its\u2019 fifth generation -called AP-MALDI (ng) HR &#8211; our AP-MALDI ion source uses several key pieces of technology MassTech has developed over years of work with this product. Furthermore, as the AP-MALDI operates at atmospheric pressure (requiring zero pumping time after installation) samples are not required to be vacuum compatible. This gives you the ability&hellip;<\/p>\n","protected":false},"author":1,"featured_media":233,"parent":73,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"footnotes":""},"class_list":["post-232","page","type-page","status-publish","has-post-thumbnail","hentry","post-has-thumbnail"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/comments?post=232"}],"version-history":[{"count":6,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/232\/revisions"}],"predecessor-version":[{"id":3092,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/232\/revisions\/3092"}],"up":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/73"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/media\/233"}],"wp:attachment":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/media?parent=232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}