What is AP-MALDI?<\/h2>\n

The AP-MALDI (Atmospheric Pressure, Matrix Assisted Laser Desorption\/Ionization) source has been our signature product since the inception of the company. Currently in its\u2019 fifth generation -called AP-MALDI (ng) HR – our AP-MALDI ion source uses several key pieces of technology MassTech has developed over years of work with this product. Furthermore, as the AP-MALDI operates at atmospheric pressure (requiring zero pumping time after installation) samples are not required to be vacuum compatible. This gives you the ability to use volatile or semi-volatile solvents and matrices in your sample, allowing for new and non-traditional MALDI applications.<\/p>\n

The AP-MALDI source is compatible with Mass Spectrometers from all major Mass Spectrometer manufacturers. Due to the atmospheric pressure interface, you can switch from ESI to AP-MALDI in minutes, if not seconds! For labs with occasional MALDI needs, or for labs without a dedicated MALDI Mass Spectrometer, the AP-MALDI source is the perfect solution.<\/p>\n

At MassTech, we have developed applications using the AP-MALDI in conjunction with instruments with MS\/MS capabilities, such as our own MT Explorer 50, allowing us to do MALDI MS\/MS and do work such as detection and even identification of bacteria and other biological samples. If your instrument has accurate mass measurement capability, with the AP-MALDI you can do accurate mass MALDI. As a result, we have seen excellent results with instruments such as the Thermo QExactive Orbitrap and the latest Agilent 6000 series.<\/p>\n

The AP-MALDI is sold world-wide through our network of distributors. Within the Continental United States, you can contact us directly for a price quote. For international deliveries, all quotes requests to msms@apmaldi.com will be redirected to the appropriate distributor. Agilent representatives can contact us directly for preferential pricing. There is a one-time installation\/training fee for these units.<\/p>\n

What is HR?\u00a0 UHR?\u00a0 (ng)?<\/h2>\n

The current AP\/MALDI is on its fifth generation.\u00a0 Along with improvements such as a solid state Nd:YAG laser, which should last for well over a decade, we have focused on usability and ease of installation with the Next Generation (ng) AP\/MALDI.<\/p>\n

Those improvements include: an internally stored solid state laser and laser controller.\u00a0 Enhanced accuracy micro-step stages.\u00a0 Externally mounted controls for laser focus and position as well as camera focus and position.\u00a0 Enhanced optical components to produce smaller spot sizes.<\/p>\n

The difference between HR and UHR is with the optical package installed in the system.\u00a0 The UHR optical package allows for sub-10 micron laser dot size (imaging resolution).\u00a0 The HR optical package can focus up to 50 micron.\u00a0 For work that does not require sub-10 micron resolution, the HR package is an economical option that provides the user with every other improvement that the Next Generation platform delivers.<\/p>\n

Why select AP MALDI?<\/h2>\n

\n
• It is the most cost effective way to do MALDI MS\/MS<\/li>\n
• It is sensitive – users can detect peptides at attmole level<\/li>\n
• Easily interchangeable with ESI in just minutes<\/li>\n
• \u201cSofter\u201d ionization (i.e., mostly +1 charge ions produced) due to fast thermalization of internal energies at atmospheric conditions<\/li>\n
• High throughput applications<\/li>\n
• Lower lifetime ownership cost<\/li>\n<\/ul>\n

  Compatible with<\/h2>\n

  \n
  • Agilent<\/li>\n
  • Bruker<\/li>\n
  • JEOL<\/li>\n
  • Sciex<\/li>\n
  • Shimadzu<\/li>\n
  • Thermo<\/li>\n
  • Waters<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

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