{"id":159,"date":"2017-03-30T01:19:11","date_gmt":"2017-03-30T01:19:11","guid":{"rendered":"http:\/\/apmaldi.com\/main\/?page_id=159"},"modified":"2025-06-14T02:16:09","modified_gmt":"2025-06-14T02:16:09","slug":"applications","status":"publish","type":"page","link":"https:\/\/www.apmaldi.com\/main\/publications\/applications\/","title":{"rendered":"Applications"},"content":{"rendered":"

Numerous publications have been made on AP\/MALDI since its introduction in Analytical Chemistry by Laiko and co-workers in 2000. Compiled here is a list of AP-MALDI related publications, divided into two groups: peer-reviewed journal articles, and poster\/conference presentations. Please feel free to e-mail us at msms@apmaldi.com<\/a> if you think we have overlooked a publication(s).<\/p>\n

Poster\/Conference Presentations<\/h2>\n

Metabolite Imaging: The Next Frontier in Spatial Biology<\/em>, Gary J. Patti, Washington Univ. Panome Bio, Breakfast Seminar ASMS 2025 PDF<\/a><\/p>\n

Application of Targeted Mass Spectrometry Imaging in the Pharmaceutical Industry<\/em>, Andrew Bowman*, Junhai Yang, Alena Joignant, Chris Good, David Wagner, and Nari Talaty, AbbVie QTAS Drug Metabolism and Disposition, Breakfast Seminar ASMS 2025 PDF<\/a><\/p>\n

AP\/MALDI coupled to Orbitrap instruments: recent developments<\/em>, Gilles Frache, Luxembourg Institute of Science and Technology, Breakfast Seminar ASMS 2025 PDF<\/a><\/p>\n

Quadrupole Ion Trap Technology: Historical Notes<\/em>, Vladimir M. Doroshenko, Masstech Inc, Breakfast seminar ASMS 2025 PDF<\/a><\/p>\n

Navy Applications of Field Portable Analysis by 3D-Printed Cone Spray Ionization Mass Spectrometry<\/em>, Patrick W. Fedick, Ph.D. Research Department, Chemistry Division, Analytical Branch Breakfast Seminar ASMS 2025 PDF<\/a><\/p>\n

Is my sushi fresh? Scombroid fish poisoning, or histamine fish poisoning, <\/em>Enrico Davoli, Universit\u00e0 di Torino, Torino and Istituto Mario Negri, Milano, breakfast seminar ASMS 2025 PDF<\/a><\/p>\n

MT Explorer 30 (MTE30) and Practical Aspects of MS Miniaturization<\/em>, Vladimir M. Doroshenko, MassTech Inc. ASMS 2022 PDF<\/a><\/p>\n

The use of AP-MALDI for structural insight into viral envelope lipids and other biomedical applications<\/em>, Jace W. Jones, Ph.D., UMD, MassTech Inc. Breakfast Seminar ASMS 2022 PDF<\/a><\/p>\n

Quantitative multiple reaction monitoring (MRM) of toxic metabolite aflatoxin-M1 from milk sampleswith atmospheric pressure matrix-assisted laser desorption\/ionization (AP\/MALDI)<\/em>, Vishal Mahale1,2<\/sup>, Madhuri Gupta1,2<\/sup>, Manisha Dhanshetty3<\/sup>, Subodh Chawan2<\/sup>, Kaushik Banerjee3<\/sup>, Nivedita Bhattacharya1,2<\/sup> and Venkateswarlu Panchagnula1,2<\/sup>, ASMS 2021. Affiliations: 1. Barefeet Analytics-MassTech demo lab, 2. MassTech Inc, 3. National Reference Laboratory, ICAR-National Research Centre for Grapes, India PDF<\/a><\/p>\n

Sensitive AP\/MALDI multiple reaction monitoring and imaging (MRMi) of acyclovir from tissue<\/em>, Vishal Mahale1,2<\/sup>, Madhuri Gupta1,2<\/sup>, Konstantin Novoselov2<\/sup>, Subodh Chawan2<\/sup>, Nivedita Bhattacharya1,2<\/sup> and Venkateswarlu Panchagnula1,2<\/sup>, ASMS2021, Affiliations: 1. Barefeet Analytics-MassTech demo lab, 2. MassTech Inc PDF<\/a><\/p>\n

AP-MALDI HRMS Analysis and Imaging at LIST MassTech’s European Demo and Application Lab<\/em>, Dr. Gilles Frache, Materials Research and Technology Department, Luxembourg Institute of Science and Technology (LIST), Luxembourg, MassTech Inc. Breakfast Seminar ASMS 2019 PDF<\/a><\/p>\n

Imaging of Gangliosides using 2,6-Dihydroxyacetophenone with an AP-MALDI Source<\/em>, Dr. Amina Woods, NIDA-IRP, NIH Baltimore, MD. MassTech Inc. Breakfast Seminar ASMS 2019 PDF<\/a><\/p>\n

AP MALDI-Quadrupole-Orbitrap MS Platform for High Spatial and High Mass Spectral Resolution In Situ Analysis of Biomolecules<\/em>, Prof. Lingjun Li, University of Wisconsin-Madison, Madison, WI. MassTech Inc. Breakfast Seminar ASMS 2019 PDF<\/a><\/p>\n

Atmospheric pressure MALDI imaging Orbitrap MS using a Masstech AP\/MALDI UHR ion source<\/em>, Gilles Frache, Dana El Assad, Materials Research and Technology Department, Luxembourg Institute of Science and Technology (LIST), Luxembourg PDF<\/a><\/p>\n

Mass Spectrometry Imaging in skin with AP-MALDI and TOF-SIMS<\/em>, Dana El Assad, C\u00e9cile Martias, Gilles Frache, Materials Research and Technology Department, Luxembourg Institute of Science and Technology (LIST), Luxembourg PDF<\/a><\/p>\n

AP MALDI \u2013 High throughput companion in food authenticity analysis<\/em>, National Chemical Laboratory (India), Venkat Panchagnula, 2018 PDF<\/a><\/p>\n

High-Resolution Tissue Imaging Using Subatmospheric and Atmospheric MALDI sources<\/em>, Eugene Moskovets1<\/sup>, Shelley N. Jackson2<\/sup>, Ludovic Muller2<\/sup>, Damon Barbacci2<\/sup>, Vladimir Doroshenko1<\/sup>, J. Albert Schultz2<\/sup>, Amina S. Woods2<\/sup>, 288910, Proceedings of the 65th<\/sup> ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, June 4-8, 2017. Affiliations: 1. MassTech Inc, Columbia, MD. 2. NIDA-IRP, NIH Baltimore, MD PDF<\/a><\/p>\n

A High Resolution Atmospheric Pressure MALDI-Quadrupole-Orbitrap Platform Enables In Situ Analysis Of Biomolecules By Multi-Mode Ionization And Acquisition<\/em>, Bingming Chen, Chuanzi OuYang, Zichuan Tian, Meng Xu, Lingjun Li, 287180, Proceedings of the 65th<\/sup> ASMS Conference on Mass Spectrometry and Allied Topics, Indianapolis, IN, June 4-8, 2017. Affiliations: University of Wisconsin-Madison, Madison, WI PDF<\/a><\/p>\n

Characterization of chemical noise in AP MALDI using LTQ and Orbitrap mass spectrometer<\/em>, Eugene Moskovets1<\/sup>, Vladimir M Doroshenko1<\/sup>, Shelley N Jackson2<\/sup>, Amina S Woods2<\/sup>, 279983, Proceedings of the 64th ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, Texas, 2016. Affiliations: 1. MassTech Inc, Columbia, MD. 2. NIDA-IRP, NIH Baltimore, MD PDF<\/a><\/p>\n

A comparison of performance characteristics of atmospheric pressure and low-pressure matrix assisted laser desorption ionization sources<\/em>, Vladimir M Doroshenko, Victor Laiko, Eugene Moskovets, 279985, Proceedings of the 64th ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, Texas, 2016. Affiliations: MassTech Inc, Columbia, MD PDF<\/a><\/p>\n

A Field Deployable Ion Trap Mass Spectrometer with Atmospheric Pressure Interface<\/em>, presented at the 9th Harsh-Environment Mass Spectrometry Workshop HEMS-2013 PDF<\/a><\/p>\n

Performance characteristics of an AP MALDI ion source applied to second generation Exactive Mass Spectrometer<\/em>, Maciej P Bromirski, Olaf Scheibner, Tabiwang N.Arrey, Kerstin Strupat, 249604, Proceedings of the 60th ASMS Conference on Mass Spectrometry and Allied Topics, Vancouver, Canada, 2012. Affiliations: Thermo Fisher Scientific GmbH, Bremen, Germany PDF<\/a><\/p>\n

MT Explorer 50 Ion Trap Mass Spectrometer with AP MALDI Ion Source<\/em>, MassTech Poster PDF<\/a><\/p>\n

MT Explorer 50 Ion Trap Mass Spectrometer with DART Ion Source<\/em>, MassTech PDF<\/a><\/p>\n

Application Notes from MassTech<\/h2>\n

Analysis of explosives, drugs, pesticides and chemical warfare simulants using Direct Sampling Atmospheric Pressure (DSAP) source with APCI and sESI modules coupled to MT Explorer 30 (MTE30) Mass Spectrometer,<\/em> Victor Laiko1<\/sup>, Madhuri Gupta2<\/sup>, Nivedita Bhattacharya2<\/sup>, and Vladimir M. Doroshenko1<\/sup>. 1. MassTech Inc, 2. Barefeet Analytics Pvt. Ltd. & MassTech LAS Application Development Laboratory PDF<\/a><\/p>\n

Mass spectral imaging using AP MALDI ionization source coupled with <\/em>Sciex\u00ae QTOF 6600 analyzer,<\/em> Vishal Mahale1<\/sup>, Madhuri Gupta1<\/sup>, Subodh Chawan2<\/sup>, Konstantin Novoselov3<\/sup> and Venkateswarlu Panchagnula1<\/sup>. 1. Barefeet Analytics Private Limited, 2. Scientia Life Technologies LLP, 3. MassTech Inc. PDF<\/a><\/p>\n

Comparison of AP-MALDI\/MS with SubAP-MALDI (1 Torr) Mass Spectrometry<\/em>, Application Note #1601, MassTech Inc, Columbia, MD PDF<\/a><\/p>\n

Tissue Analysis and Imaging Using APMALDI(ng) UHR Ion Source with LTQ Orbitrap Velos<\/em>, Ludovic Muller1<\/sup>, Shelley Jackson1<\/sup>, Aurelie Roux1<\/sup>, Amina S. Woods1<\/sup>, Berk Oktem, Application Note #1504. 1. National Institute on Drug Abuse, National Institutes of Health, 2. MassTech Inc, Columbia, MD PDF<\/a><\/p>\n

Using APMALDI-HR Ion source on Thermo Orbitrap Fusion and TSQ Quantiva Mass Spectrometers for Peptide Analysis and Imaging<\/em>, Berk Oktem, Application Note #1402, MassTech Inc, Columbia, MD, USA PDF<\/a><\/p>\n

Using AP-MALDI on an AB Sciex Triple-TOF 5600 System<\/em>, Berk Oktem, Application Note #1401, MassTech Inc, Columbia, MD PDF<\/a><\/p>\n

Analysis of Microorganisms by Atmospheric Pressure Matrix Assisted Laser Desorption\/Ionization and MT Explorer 100 Ion Trap Mass Spectrometer<\/em>, Appavu Sundaram, Jane Razumovski, Berk Oktem, Jianhua Tang, Vladimir Doroshenko, Application Note #1201, MassTech Inc, Columbia, MD PDF<\/a><\/p>\n

Agilent Specific AP\/MALDI Publications<\/h2>\n

Versatile Protein Identification Using AP-MALDI Ion Trap Mass Spectrometry<\/em>, Jose E. Meza, Donghui Yi, Christine A. Miller and Patrick D. Perkins, PharmaGenomics November\/December 2003. Affiliations: Agilent Technologies PDF<\/a><\/p>\n

Comparison of Sensitivity and Spectra between the AP-MALDI LC\/MSD Trap SL System and Traditional Vacuum MALDI-TOF<\/em>, Patrick Perkins, Jian Bai, Viorica Lopez-Avila,
and Christine Miller, Application Note, Agilent Technologies PDF<\/a><\/p>\n

Agilent MALDI Protein Identification Solution<\/em>, MS Application Guide, Agilent Technologies PDF<\/a><\/p>\n

AP\/MALDI on Agilent Mass Spectrometers<\/em>, Presentation, 2009 PDF<\/a><\/p>\n

Thermo Scientific Specific AP\/MALDI Publications<\/h2>\n

Biological Applications of AP MALDI with Thermo Scientific Exactive Orbitrap MS<\/em>, Kerstin Strupat, Olaf Scheibner, Tabiwang Arrey, Maciej Bromirski, Application Note #30224, Thermo Fisher Scientific, Bremen, Germany PDF<\/a><\/p>\n

Sample Preparation Links<\/h2>\n

MALDI-TOF Sample Preparation Guide from MIT<\/a><\/p>\n

Some recent AP\/MALDI-related journal articles<\/h2>\n

Li G, Cao Q, Liu Y, et al. (2018) “Characterizing and Alleviating Ion Suppression Effects in Atmospheric Pressure Matrix-Assisted Laser Desorption\/Ionization (AP-MALDI)”<\/em>, Rapid Commun Mass Spectrom, https:\/\/doi.org\/10.1002\/rcm.8358<\/a><\/p>\n

Agrawal K and Wu HF (2008), “Bare silica nanoparticles as concentrating and affinity probes for rapid analysis of aminothiols, lysozyme and peptide mixtures using atmospheric-pressure matrix-assisted laser desorption\/ionization ion trap and matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry”<\/em>, Rapid Commun. Mass Spectrom.. Vol. 22(3), pp. 283-290.<\/p>\n

Agrawal K, Wu HF and Shrivas K (2008), “Reverse micellar microextraction for rapid analysis of thiol-containing peptides and amino acids by atmospheric-pressure matrix-assisted laser desorption\/ionization ion trap and matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry”<\/em>, Rapid Commun. Mass Spectrom.., May, 2008. Vol. 22(9), pp. 1437-1444.<\/p>\n

Berkout VD, Kryuchkov SI and Doroshenko VM (2007), “Modeling of ion processes in atmospheric pressure matrix-assisted laser desorption\/ionisation”<\/em>, Rapid Commun. Mass Spectrom.. Vol. 21(13), pp. 2046-2050.<\/p>\n

Chong S-L, Nissil\u00e4 T, Ketola RA, Koutaniemi S, Derba-Maceluch M, Mellerowicz EJ, Tenkanen M and Tuomainen P (2011), “Feasibility of using atmospheric pressure matrix-assisted laser desorption\/ionization with ion trap mass spectrometry in the analysis of acetylated xylooligosaccharides derived from hardwoods and Arabidopsis thaliana “<\/em>, Analytical and Bioanalytical Chemistry. Vol. 401(9), pp. 2995.<\/p>\n

Creaser CS, Green PS, Kilby PM and Ratcliffe L (2006), “Capillary liquid chromatography\/atmospheric-pressure matrix-assisted laser desorption\/ionisation ion trap mass spectrometry: a comparison with liquid chromatography\/matrix-assisted laser desorption\/ionisation time-of-flight and liquid chromatography\/electrospray ionisation quadrupole time-of-flight for the identification of tryptic peptides”<\/em>, Rapid Commun. Mass Spectrom.. Vol. 20(5), pp. 829-836.<\/p>\n

Daniel JM, Laiko VV, Doroshenko VM and Zenobi R (2005), “Interfacing liquid chromatography with atmospheric pressure MALDI-MS”<\/em>, Anal Bioanal Chem., Nov, 2005. Vol. 383(6), pp. 895-902.<\/p>\n

Grasso G, Fragai M, Rizzarelli E, Spoto G and Yeo KJ (2006), “In situ AP\/MALDI-MS characterization of anchored matrix metalloproteinases”<\/em>, J Mass Spectrom., Dec, 2006. Vol. 41(12), pp. 1561-1569.<\/p>\n

Grasso G, Rizzarelli E and Spoto G (2007), “AP\/MALDI-MS complete characterization of the proteolytic fragments produced by the interaction of insulin degrading enzyme with bovine insulin”<\/em>, J Mass Spectrom., Dec, 2007. Vol. 42(12), pp. 1590-1598.<\/p>\n

Gudlavalleti SK, Sundaram AK, Razumovski J and Doroshenko V (2008), “Application of atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry for rapid identification of Neisseria species”<\/em>, J Biomol Tech., Jul, 2008. Vol. 19(3), pp. 200-204.<\/p>\n

Hanton SD, Parees DM and Zweigenbaum J (2006), “The Fragmentation of Ethoxylated Surfactants by AP-MALDI-QIT “<\/em>, Journal of the American Society for Mass Spectrometry . Vol. 17(3), pp. 453 – 458.<\/p>\n

Hsieh S, Ku HY, Ke YT and Wu HF (2007), “Self-assembled-monolayer-modified silicon substrate to enhance the sensitivity of peptide detection for AP-MALDI mass spectrometry”<\/em>, J Mass Spectrom., Dec, 2007. Vol. 42(12), pp. 1628-1636.<\/p>\n

Ito E, Tominaga A, Waki H, Miseki K, Tomioka A, Nakajima K, Kakehi K, Suzuki M, Taniguchi N and Suzuki A (2012), “Structural Characterization of Monosialo-, Disialo- and Trisialo-gangliosides by Negative Ion AP-MALDI-QIT-TOF Mass Spectrometry with MSn Switching”<\/em>, Neurochemical Research. Vol. 37(6), pp. 1315-1324.<\/p>\n

Kassler A, Pittenauer E, Doerr N and Allmaier G (2009), “Electrospray ionization and atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry of antioxidants applied in lubricants”<\/em>, Rapid Commun. Mass Spectrom.., Dec, 2009. Vol. 23(24), pp. 3917-3927.<\/p>\n

Kellersberger KA, Yu ET, Merenbloom SI and Fabris D (2005), “Atmospheric pressure MALDI-FTMS of normal and chemically modified RNA\\ “<\/em>, Journal of the American Society for Mass Spectrometry . Vol. 16(2), pp. 199 – 207.<\/p>\n

Konn DO, Murrell J, Despeyroux D and Gaskell SJ (2005), “Comparison of the effects of ionization mechanism, analyte concentration, and ion “cool-times” on the internal energies of peptide ions produced by electrospray and atmospheric pressure matrix-assisted laser desorption ionization”<\/em>, J. Am. Soc. Mass Spectrom.., May, 2005. Vol. 16(5), pp. 743-751.<\/p>\n

Levander F and James P (2005), “Automated protein identification by the combination of MALDI MS and MS\/MS spectra from different instruments”<\/em>, J. Proteome Res.. Vol. 4(1), pp. 71-74.<\/p>\n

Li Y, Shrestha B and Vertes A (2008), “Atmospheric pressure infrared MALDI imaging mass spectrometry for plant metabolomics”<\/em>, Anal. Chem.., Jan, 2008. Vol. 80(2), pp. 407-420.<\/p>\n

Li Y, Shrestha B and Vertes A (2007), “Atmospheric pressure molecular imaging by infrared MALDI mass spectrometry”<\/em>, Anal. Chem.., Jan, 2007. Vol. 79(2), pp. 523-532.<\/p>\n

Mayrhofer C, Krieger S, Raptakis E and Allmaier G (2006), “Comparison of vacuum matrix-assisted laser desorption\/ionization (MALDI) and atmospheric pressure MALDI (AP-MALDI) tandem mass spectrometry of 2-dimensional separated and trypsin-digested glomerular proteins for database search derived identification”<\/em>, J. Proteome Res.., Aug, 2006. Vol. 5(8), pp. 1967-1978.<\/p>\n

McEwen CN, Larsen BS and Trimpin S (2010), “Laserspray Ionization on a Commercial Atmospheric Pressure-MALDI Mass Spectrometer Ion Source: Selecting Singly or Multiply Charged Ions”<\/em>, Analytical Chemistry. Vol. 82(12), pp. 4998-5001.<\/p>\n

Navare A, Nouzova M, Noriega FG, Hern\u00e1ndez-Mart\u00ednez S, Menzel C and Fern\u00e1ndez FM (2009), “On-chip solid-phase extraction pre-concentration\/focusing substrates coupled to atmospheric pressure matrix-assisted laser desorption\/ionization ion trap mass spectrometry for high sensitivity biomolecule analysis”<\/em>, Rapid Communications in Mass Spectrometry. Vol. 23(4), pp. 477-486. John Wiley & Sons, Ltd..<\/p>\n

Navare AT and Fern\u00e1ndez FM (2010), “Inline pneumatically assisted atmospheric pressure matrix-assisted laser desorption\/ionization ion trap mass spectrometry”<\/em>, Journal of Mass Spectrometry. Vol. 45(6), pp. 635-642. Wiley Online Library.<\/p>\n

Nguyen J and Russell SC (2010), “Targeted Proteomics Approach to Species-Level Identification of Bacillus thuringiensis Spores by AP-MALDI-MS “<\/em>, Journal of the American Society for Mass Spectrometry . Vol. 21(6), pp. 993 – 1001.<\/p>\n

Pihlainen K, Grigoras K, Franssila S, Ketola R, Kotiaho T and Kostiainen R (2005), “Analysis of amphetamines and fentanyls by atmospheric pressure desorption\/ionization on silicon mass spectrometry and matrix-assisted laser desorption\/ionization mass spectrometry and its application to forensic analysis of drug seizures”<\/em>, J Mass Spectrom., Apr, 2005. Vol. 40(4), pp. 539-545.<\/p>\n

Pittenauer E, Kassler A, Haubner R and Allmaier G (2011), “Different target surfaces for the analysis of peptides, peptide mixtures and peptide mass fingerprints by AP-MALDI ion trap-mass spectrometry”<\/em>, Journal of Proteomics. Vol. 74(7), pp. 975-981.<\/p>\n

Pittenauer E, Zehl M, Belgacem O, Raptakis E, Mistrik R and Allmaier G (2006), “Comparison of CID spectra of singly charged polypeptide antibiotic precursor ions obtained by positive-ion vacuum MALDI IT\/RTOF and TOF\/RTOF, AP-MALDI-IT and ESI-IT mass spectrometry”<\/em>, J Mass Spectrom., Apr, 2006. Vol. 41(4), pp. 421-447.<\/p>\n

Rapp E, Charvat A, Beinsen A, Plessmann U, Reichl U, Seidel-Morgenstern A, Urlaub H and Abel B (2009), “Atmospheric pressure free liquid infrared MALDI mass spectrometry: toward a combined ESI\/ MALDI-liquid chromatography interface”<\/em>, Anal. Chem.., Jan, 2009. Vol. 81(1), pp. 443-452.<\/p>\n

Remes PM and Glish GL (2009), “On the time scale of internal energy relaxation of AP-MALDI and nano-ESI ions in a quadrupole ion trap”<\/em>, J. Am. Soc. Mass Spectrom.., Oct, 2009. Vol. 20(10), pp. 1801-1812.<\/p>\n

Sabu S, Yang FC, Wang YS, Chen WH, Chou MI, Chang HC and Han CC (2007), “Peptide analysis: solid phase extraction-elution on diamond combined with atmospheric pressure matrix-assisted laser desorption\/ionization-Fourier transform ion cyclotron resonance mass spectrometry”<\/em>, Anal. Biochem.., Aug, 2007. Vol. 367(2), pp. 190-200.<\/p>\n

Salo PK, Salomies H, Harju K, Ketola RA, Kotiaho T, Yli-Kauhaluoma J and Kostiainen R (2005), “Analysis of Small Molecules by Ultra Thin-Layer Chromatography-Atmospheric Pressure Matrix-Assisted Laser Desorption\/Ionization Mass Spectrometry “<\/em>, Journal of the American Society for Mass Spectrometry . Vol. 16(6), pp. 906 – 915.<\/p>\n

Salo PK, Vilmunen S, Salomies H, Ketola RA and Kostiainen R (2007), “Two-dimensional ultra-thin-layer chromatography and atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry in bioanalysis”<\/em>, Anal. Chem.., Mar, 2007. Vol. 79(5), pp. 2101-2108.<\/p>\n

Schneider BB, Lock C and Covey TR (2005), “AP and vacuum MALDI on a QqLIT instrument”<\/em>, J. Am. Soc. Mass Spectrom.., Feb, 2005. Vol. 16(2), pp. 176-182.<\/p>\n

Schulz E, Karas M, Rosu F and Gabelica V (2006), “Influence of the matrix on analyte fragmentation in atmospheric pressure MALDI”<\/em>, J. Am. Soc. Mass Spectrom.., Jul, 2006. Vol. 17(7), pp. 1005-1013.<\/p>\n

Sekar R and Wu HF (2006), “Quantitative method for analysis of monensin in soil, water, and urine by direct combination of single-drop microextraction with atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry”<\/em>, Anal. Chem.., Sep, 2006. Vol. 78(18), pp. 6306-6313.<\/p>\n

Shrestha B, Nemes P, Nazarian J, Hathout Y, Hoffman EP and Vertes A (2010), “Direct analysis of lipids and small metabolites in mouse brain tissue by AP IR-MALDI and reactive LAESI mass spectrometry”<\/em>, Analyst. Vol. 135, pp. 751-758. The Royal Society of Chemistry.<\/p>\n

Shrivas K and Wu HF (2008), “Applications of silver nanoparticles capped with different functional groups as the matrix and affinity probes in surface-assisted laser desorption\/ionization time-of-flight and atmospheric pressure matrix-assisted laser desorption\/ionization ion trap mass spectrometry for rapid analysis of sulfur drugs and biothiols in human urine”<\/em>, Rapid Commun. Mass Spectrom.., Sep, 2008. Vol. 22(18), pp. 2863-2872.<\/p>\n

Shrivas K and Wu HF (2008), “Functionalized-multiwalled carbon nanotubes as a preconcentrating probe for rapid monitoring of cationic dyestuffs in environmental water using AP-MALDI\/MS”<\/em>, J Sep Sci., Oct, 2008. Vol. 31(20), pp. 3603-3611.<\/p>\n

Shrivas K and Wu HF (2008), “Modified silver nanoparticle as a hydrophobic affinity probe for analysis of peptides and proteins in biological samples by using liquid-liquid microextraction coupled to AP-MALDI-ion trap and MALDI-TOF mass spectrometry”<\/em>, Anal. Chem.., Apr, 2008. Vol. 80(7), pp. 2583-2589.<\/p>\n

Shrivas K and Wu HF (2008), “Oxidized multiwalled carbon nanotubes for quantitative determination of cationic surfactants in water samples using atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry”<\/em>, Anal. Chim. Acta., Nov, 2008. Vol. 628(2), pp. 198-203.<\/p>\n

Shrivas K and Wu HF (2007), “A rapid, sensitive and effective quantitative method for simultaneous determination of cationic surfactant mixtures from river and municipal wastewater by direct combination of single-drop microextraction with AP-MALDI mass spectrometry”<\/em>, J Mass Spectrom., Dec, 2007. Vol. 42(12), pp. 1637-1644.<\/p>\n

Shrivas K and Wu HF (2007), “Quantitative bioanalysis of quinine by atmospheric pressure-matrix assisted laser desorption\/ionization mass spectrometry combined with dynamic drop-to-drop solvent microextraction”<\/em>, Anal. Chim. Acta., Dec, 2007. Vol. 605(2), pp. 153-158.<\/p>\n

Shrivas K and Wu HF (2007), “Single drop microextraction as a concentrating probe for rapid screening of low molecular weight drugs from human urine in atmospheric-pressure matrix-assisted laser desorption\/ionization mass spectrometry”<\/em>, Rapid Commun. Mass Spectrom.. Vol. 21(18), pp. 3103-3108.<\/p>\n

Shrivas K and Wu H-F (2008), “Applications of silver nanoparticles capped with different functional groups as the matrix and affinity probes in surface-assisted laser desorption\/ionization time-of-flight and atmospheric pressure matrix-assisted laser desorption\/ionization ion trap mass spectrometry for rapid analysis of sulfur drugs and biothiols in human urine”<\/em>, Rapid Communications in Mass Spectrometry. Vol. 22(18), pp. 2863-2872. John Wiley & Sons, Ltd..<\/p>\n

Sudhir PR, Shrivas K, Zhou ZC and Wu HF (2008), “Single drop microextraction using silver nanoparticles as electrostatic probes for peptide analysis in atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry and comparison with gold electrostatic probes and silver hydrophobic probes”<\/em>, Rapid Commun. Mass Spectrom.., Oct, 2008. Vol. 22(19), pp. 3076-3086.<\/p>\n

Sudhir PR, Wu HF and Zhou ZC (2005), “Identification of peptides using gold nanoparticle-assisted single-drop microextraction coupled with AP-MALDI mass spectrometry”<\/em>, Anal. Chem.., Nov, 2005. Vol. 77(22), pp. 7380-7385.<\/p>\n

Wang Y, Schneider BB, Covey TR and Pawliszyn J (2005), “High-performance SPME\/AP MALDI system for high-throughput sampling and determination of peptides”<\/em>, Anal. Chem.., Dec, 2005. Vol. 77(24), pp. 8095-8101.<\/p>\n

Wu HF, Ku HY and Yen JH (2008), “Liquid-phase microextraction for rapid AP-MALDI and quantitation of nortriptyline in biological matrices”<\/em>, J Sep Sci., Jul, 2008. Vol. 31(12), pp. 2288-2294.<\/p>\n

Wu HF and Lin CH (2006), “Direct combination of immersed single-drop microextraction with atmospheric pressure matrix-assisted laser desorption\/ionization tandem mass spectrometry for rapid analysis of a hydrophilic drug via hydrogen-bonding interaction and comparison with liquid-liquid extraction and liquid-phase microextraction using a dual gauge microsyringe with a hollow fiber”<\/em>, Rapid Commun. Mass Spectrom.. Vol. 20(16), pp. 2511-2515.<\/p>\n

Zhang J, Lamotte L, Dodds ED and Lebrilla CB (2005), “Atmospheric pressure MALDI Fourier transform mass spectrometry of labile oligosaccharides”<\/em>, Anal. Chem.., Jul, 2005. Vol. 77(14), pp. 4429-4438.<\/p>\n

Laiko VV, Baldwin MA and Burlingame AL (2000), “Atmospheric pressure matrix-assisted laser desorption\/ionization mass spectrometry”<\/em>, Anal. Chem.., Feb, 2000. Vol. 72(4), pp. 652-657.<\/p>\n\n\n

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  1. \nFriday - <\/span>Is my sushi fresh? Scombroid fish poisoning, or histamine fish poisoning, Enrico Davoli, Universit\u00e0 di Torino, Torino and Istituto Mario Negri, Milano, breakfast seminar ASMS 2025<\/span><\/a><\/li>\n
  2. \nFriday - <\/span>Navy Applications of Field Portable Analysis by 3D-Printed Cone Spray Ionization Mass Spectrometry, Patrick W. Fedick, Ph.D. Research Department, Chemistry Division, Analytical Branch Breakfast Seminar ASMS 2025<\/span><\/a><\/li>\n
  3. \nFriday - <\/span>Quadrupole Ion Trap Technology: Historical Notes, Vladimir M. Doroshenko, Masstech Inc, Breakfast seminar ASMS 2025<\/span><\/a><\/li>\n
  4. \nFriday - <\/span>AP\/MALDI coupled to Orbitrap instruments: recent developments, Gilles Frache, Luxembourg Institute of Science and Technology, Breakfast Seminar ASMS 2025<\/span><\/a><\/li>\n
  5. \nFriday - <\/span>Application of Targeted Mass Spectrometry Imaging in the Pharmaceutical Industry, Andrew Bowman*, Junhai Yang, Alena Joignant, Chris Good, David Wagner, and Nari Talaty, AbbVie QTAS Drug Metabolism and Disposition, Breakfast Seminar ASMS 2025<\/span><\/a><\/li>\n
  6. \nFriday - <\/span>Metabolite Imaging: The Next Frontier in Spatial Biology, Gary J. Patti, Washington Univ. Panome Bio, Breakfast Seminar ASMS 2025<\/span><\/a><\/li>\n
  7. \nThursday - <\/span>SPME analysis on a portable MS\/MS instrument, Enrico Davoli, Istituto Mario Negri, Milan, Italy - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  8. \nThursday - <\/span>Expanding Analytical Frontiers: Showcasing the Portability and Versatility of Miniature Ion Trap Mass Spectrometry, Caleigh O'Connor, MassTech Inc., MD, USA - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  9. \nThursday - <\/span>Applications of AP\/MALDI with triple quadrupole mass analyzers, Nivedita Bhattacharya, Barefeet Analytics Pvt Ltd, India - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  10. \nThursday - <\/span>Processing MassTech AP\/MALDI Data using MSiReader v2.8, Russ Kibbe, North Carolina State University, USA - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  11. \nThursday - <\/span>AP\/MALDI: Connecting a variety of mass spectrometers globally with MSI, Peter Verhaert, ProteoFormiX, Belgium - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  12. \nThursday - <\/span>AP\/MALDI coupled with Orbitraps: Principle, applications and current developments, Gilles Frache, Luxembourg Institute of Science and Technology, Luxembourg - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  13. \nThursday - <\/span>Sequential Imaging with AP\/MALDI for Enhanced Tissue Characterization, Erin Seeley, University of Texas, Austin, USA - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  14. \nThursday - <\/span>Imaging Investigations Using AP\/MALDI: Drugs and Metabolites Distribution, Alice Passoni, Istituto Mario Negri, Milan, Italy - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  15. \nThursday - <\/span>In situ deciphering protein glycosylation signatures in human ovarian cancer via combined MALDI MS imaging and tandem MS, Penghsuan (Timo) Huang, University of Wisconsin-Madison, USA - Breakfast Seminar ASMS 2024<\/span><\/a><\/li>\n
  16. \nWednesday - <\/span>MT Explorer 30 (MTE30) and Practical Aspects of MS Miniaturization, Vladimir M. Doroshenko, ASMS 2022<\/span><\/a><\/li>\n
  17. \nWednesday - <\/span>Analysis of explosives, drugs, pesticides and chemical warfare simulants using Direct Sampling Atmospheric Pressure (DSAP) source with APCI and sESI modules coupled to MT Explorer 30 (MTE30) Mass Spectrometer<\/span><\/a><\/li>\n
  18. \nTuesday - <\/span>The use of AP-MALDI for structural insight into viral envelope lipids and other biomedical applications, Jace W. Jones, Ph.D., UMD, MassTech Inc. Breakfast Seminar ASMS 2022<\/span><\/a><\/li>\n
  19. \nMonday - <\/span>Sensitive AP\/MALDI multiple reaction monitoring and imaging (MRMi) of acyclovir from tissue, Vishal Mahale, Madhuri Gupta, Konstantin Novoselov, Subodh Chawan, Nivedita Bhattacharya, and Venkateswarlu Panchagnula<\/span><\/a><\/li>\n
  20. \nMonday - <\/span>Quantitative multiple reaction monitoring (MRM) of toxic metabolite aflatoxin-M1 from milk sampleswith atmospheric pressure matrix-assisted laser desorption\/ionization (AP\/MALDI), Vishal Mahale, Madhuri Gupta, Manisha Dhanshetty, Subodh Chawan, Kaushik Banerjee, Nivedita Bhattacharya and Venkateswarlu Panchagnula<\/span><\/a><\/li>\n
  21. \nFriday - <\/span>Mass spectral imaging using AP MALDI ionization source coupled with Sciex QTOF 6600 analyzer<\/span><\/a><\/li>\n
  22. \nTuesday - <\/span>AP MALDI-Quadrupole-Orbitrap MS Platform for High Spatial and High Mass Spectral Resolution In Situ Analysis of Biomolecules, Prof. Lingjun Li, University of Wisconsin-Madison, Madison, WI. MassTech Inc. Breakfast Seminar ASMS 2019<\/span><\/a><\/li>\n
  23. \nTuesday - <\/span> AP-MALDI HRMS Analysis and Imaging at LIST MassTech's European Demo and Application Lab, Dr. Gilles Frache, Materials Research and Technology Department, Luxembourg Institute of Science and Technology (LIST), Luxembourg, MassTech Inc. Breakfast Seminar ASMS 2019<\/span><\/a><\/li>\n
  24. \nMonday - <\/span>Imaging of Gangliosides using 2,6-Dihydroxyacetophenone with an AP-MALDI Source, Dr. Amina Woods, NIDA-IRP, NIH Baltimore, MD. MassTech Inc. Breakfast Seminar ASMS 2019<\/span><\/a><\/li>\n
  25. \nWednesday - <\/span>MT Companion, portable GCMS system<\/span><\/a><\/li>\n
  26. \nTuesday - <\/span>Atmospheric pressure MALDI imaging Orbitrap MS using a Masstech AP\/MALDI UHR ion source, Gilles Frache, Dana El Assad, Materials Research and Technology Department, Luxembourg Institute of Science and Technology (LIST), Luxembourg<\/span><\/a><\/li>\n
  27. \nTuesday - <\/span>Mass Spectrometry Imaging in skin with AP-MALDI and TOF-SIMS<\/span><\/a><\/li>\n
  28. \nTuesday - <\/span>AP MALDI \u2013 High throughput companion in food authenticity analysis, Venkat Panchagnula, 2018<\/span><\/a><\/li>\n
  29. \nFriday - <\/span>Determination of Triazines and Triazoles in Grapes Using Atmospheric Pressure Matrix-Assisted Laser Desorption\/Ionization High-Resolution Mass Spectrometry<\/span><\/a><\/li>\n
  30. \nTuesday - <\/span>High Resolution Atmospheric Pressure MALDI-Quadrupole-Orbitrap Platform Enables In Situ Analysis of Biomolecules by Multi-Mode Ionization and Acquisition<\/span><\/a><\/li>\n
  31. \nTuesday - <\/span>High-resolution Tissue Imaging Using sub-Atmospheric and Atmospheric MALDI Sources<\/span><\/a><\/li>\n
  32. \nWednesday - <\/span>MassTech Inc's Standard Terms and Conditions<\/span><\/a><\/li>\n
  33. \nMonday - <\/span>SubAP-MALDI(ng) UHR JASMS Advertisement<\/span><\/a><\/li>\n
  34. \nMonday - <\/span>Automated Sample Identification in the Field by DART-MT Explorer 50 MS\/MS<\/span><\/a><\/li>\n
  35. \nMonday - <\/span>AP\/MALDI(ng) UHR Ion Source with Ion Funnel Technology<\/span><\/a><\/li>\n
  36. \nMonday - <\/span>AP\/MALDI(ng) UHR Ion Source<\/span><\/a><\/li>\n
  37. \nMonday - <\/span>MT Explorer 50<\/span><\/a><\/li>\n
  38. \nMonday - <\/span>IFT Injector Interface for Mass Spectrometers<\/span><\/a><\/li>\n
  39. \nMonday - <\/span>The-LCP thermo-stabilized platform for high-temperature nanoLC separations<\/span><\/a><\/li>\n
  40. \nFriday - <\/span>Performance Characteristics of an AP MALDI Ion Source Applied to Exactive Plus Mass Spectrometer<\/span><\/a><\/li>\n
  41. \nFriday - <\/span>Characterization of chemical noise in AP MALDI using LTQ and Orbitrap mass spectrometer<\/span><\/a><\/li>\n
  42. \nFriday - <\/span>A Field Deployable Ion Trap Mass Spectrometer with Atmospheric Pressure Interface <\/span><\/a><\/li>\n
  43. \nFriday - <\/span> MT Explorer 50 Ion Trap Mass Spectrometer with AP MALDI Ion Source<\/span><\/a><\/li>\n
  44. \nFriday - <\/span>MT Explorer 50 Ion Trap Mass Spectrometer with DART Ion Source<\/span><\/a><\/li>\n
  45. \nFriday - <\/span>Analysis of Microorganisms by Atmospheric Pressure Matrix Assisted Laser Desorption\/Ionization and MT Explorer 100 Ion Trap Mass Spectrometer<\/span><\/a><\/li>\n
  46. \nFriday - <\/span>Using AP-MALDI on an AB Sciex Triple-TOF 5600 System<\/span><\/a><\/li>\n
  47. \nFriday - <\/span>Using APMALDI-HR Ion source on Thermo Orbitrap Fusion and TSQ Quantiva Mass Spectrometers for Peptide Analysis and Imaging <\/span><\/a><\/li>\n
  48. \nFriday - <\/span>Tissue Analysis and Imaging Using APMALDI(ng) UHR Ion Source with LTQ Orbitrap Velos<\/span><\/a><\/li>\n
  49. \nFriday - <\/span>Comparison of AP-MALDI\/MS with SubAP-MALDI (1 Torr) Mass Spectrometry<\/span><\/a><\/li>\n
  50. \nFriday - <\/span>Versatile Protein Identification Using AP-MALDI Ion Trap Mass Spectrometry<\/span><\/a><\/li>\n
  51. \nFriday - <\/span>Comparison between traditional Vacuum MALDI TOF and AP\/MALDI Ion Trap System<\/span><\/a><\/li>\n
  52. \nFriday - <\/span>Agilent MALDI Protein Identification Solution<\/span><\/a><\/li>\n
  53. \nFriday - <\/span>AP\/MALDI on Agilent Mass Spectrometers<\/span><\/a><\/li>\n
  54. \nFriday - <\/span>Biological Applications of AP MALDI with Thermo Scientific Exactive Orbitrap MS<\/span><\/a><\/li>\n
  55. \nFriday - <\/span>SubAP-MALDI(ng) UHR<\/span><\/a><\/li>\n
  56. \nFriday - <\/span>AP-MALDI(ng) with Ion Funnel<\/span><\/a><\/li>\n
  57. \nFriday - <\/span>MT Explorer 50 Ion Trap Mass Spectrometer with MassTech's D\/S APCI Ion Source<\/span><\/a><\/li>\n
  58. \nFriday - <\/span>MT Explorer 50 Ion Trap Mass Spectrometer with MassTech's D\/S sESI Ion Source<\/span><\/a><\/li>\n
  59. \nFriday - <\/span>MT Explorer 50 Ion Trap Mass Spectrometer<\/span><\/a><\/li>\n
  60. \nFriday - <\/span>MT Explorer 50 Ion Trap Mass Spectrometer with MassTech's AP\/MALDI Ion Source<\/span><\/a><\/li>\n
  61. \nFriday - <\/span>MT Explorer 50 Ion Trap Mass Spectrometer with DART Ion Source<\/span><\/a><\/li>\n
  62. \nFriday - <\/span>MT Explorer 100 Ion Trap Mass Spectrometer - discontinued<\/span><\/a><\/li>\n
  63. \nFriday - <\/span>Ion Funnel Interface For Mass Spectrometer<\/span><\/a><\/li>\n
  64. \nFriday - <\/span>TheLCP Thermo-stabilized LC Platform<\/span><\/a><\/li>\n
  65. \nFriday - <\/span>Chromexplorer <\/span><\/a><\/li>\n
  66. \nFriday - <\/span>MODAS<\/span><\/a><\/li>\n
  67. \nThursday - <\/span> A comparison of performance characteristics of AP and low-pressure (SubAP) MALDI sources<\/span><\/a><\/li>\n<\/ol><\/div>
    <\/div><\/div>\n\n\n\n

    <\/p>\n","protected":false},"excerpt":{"rendered":"

    Numerous publications have been made on AP\/MALDI since its introduction in Analytical Chemistry by Laiko and co-workers in 2000. Compiled here is a list of AP-MALDI related publications, divided into two groups: peer-reviewed journal articles, and poster\/conference presentations. Please feel free to e-mail us at msms@apmaldi.com if you think we have overlooked a publication(s). Poster\/Conference Presentations Metabolite Imaging: The Next Frontier in Spatial Biology, Gary J. Patti, Washington Univ. Panome Bio, Breakfast Seminar ASMS 2025 PDF Application of Targeted Mass…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":77,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"footnotes":""},"class_list":["post-159","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/159","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/comments?post=159"}],"version-history":[{"count":46,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/159\/revisions"}],"predecessor-version":[{"id":4375,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/159\/revisions\/4375"}],"up":[{"embeddable":true,"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/pages\/77"}],"wp:attachment":[{"href":"https:\/\/www.apmaldi.com\/main\/wp-json\/wp\/v2\/media?parent=159"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}